Neurology, stroke and radiology · FICTIONAL CASE

Wake-up stroke: the clock is uncertain, but the pathway is not closed

Separate last-known-well time from discovery time, obtain the right imaging and avoid excluding reperfusion options prematurely.

Time-critical imaging and reperfusion reasoning16 minutes0/3 decisions explored
PAUSE BEFORE USING

This is educational content, not a clinical protocol. Verify current guidance, use local pathways and seek appropriate senior or specialist help.

THE CASE

A fictional 66-year-old wakes with aphasia and right-sided weakness. They were last known well eight hours earlier, have disabling deficits and are not taking anticoagulants.

01 · INITIAL PRESENTATION

Listen for the assumption.

SHO

Because the exact onset exceeds the usual thrombolysis window, I thought reperfusion was no longer possible.

Registrar

Which treatment decision still depends on vascular and tissue imaging?

SHO

Thrombectomy may remain possible in selected patients up to 24 hours from last known well, so the stroke pathway and appropriate imaging must continue urgently.

WHERE IS THE CONSULTANT?

Choose an answer below and reveal the reasoning to see consultant feedback at every checkpoint. The full consultant-led synthesis follows after all three decisions.

Go to the first decision ↓
EVOLVING INFORMATION

The picture develops.

  1. Non-contrast CT shows no intracranial haemorrhage
  2. CTA shows proximal anterior-circulation occlusion
  3. Perfusion imaging suggests salvageable brain tissue and a limited core
02 · DECISION CHECKPOINTS

Commit before you reveal.

After you select an option, reveal the model reasoning and the consultant’s feedback.

DECISION 1What is the key timing statement for handover?
DECISION 2Which imaging should follow when thrombectomy may be indicated?
DECISION 3Who should make the reperfusion decision?
03 · CONSULTANT-LED SYNTHESIS

Hear the senior team refine the plan.

The registrar tests the plan, the consultant synthesises the key principle, and the SHO confirms the safer next steps.

Registrar

We should confirm glucose, blood pressure, baseline function, bleeding risks and mimics without delaying the stroke pathway.

Consultant

Exactly. Unknown onset changes the selection process; it does not justify abandoning time-critical assessment.

SHO

I will communicate last known well, discovery, deficit severity, imaging sequence and specialist decision status.

CLINORA DECISION TRACE
01 · CUEDisabling wake-up stroke with proximal occlusion
02 · INTERPRETPotential extended-window thrombectomy candidate
03 · ACTUrgent stroke activation, vascular/tissue imaging and specialist reperfusion decision
SAFETY CHECK

What must remain explicit.

  • Use the current regional stroke pathway.
  • Record last-known-well and discovery times separately.
  • Do not delay transfer or thrombectomy discussion for non-essential tests.
COMMON ERRORS

Where reasoning fails.

  • Treating wake-up time as onset time
  • Stopping after a non-contrast CT
  • Assuming every extended-window occlusion is automatically eligible
STRUCTURED HANDOVER
Acute disabling stroke: last known well [time], discovered [time], deficit [summary], baseline [summary], anticoagulation/glucose/BP [details], imaging [findings] and thrombectomy discussion [status].
REFLECTIVE PAUSE

How would you prevent an uncertain timeline from becoming an inaccurate fixed time during successive handovers?