Gastroenterology · FREE GUIDE

Acute decompensated cirrhosis

Identify the precipitant and organ failures early while using a structured first-hours cirrhosis pathway.

PAUSE BEFORE USING

This is an educational summary, not a point-of-care protocol. Follow current local emergency and medicines guidance and seek senior/specialist support.

FICTIONAL SCENARIO

A fictional 59-year-old with cirrhosis presents with increasing ascites, jaundice, confusion and reduced urine output.

01 · RECOGNISE

Frame the danger first.

  • Acute decompensation may present with ascites, encephalopathy, bleeding, infection, jaundice or renal dysfunction.
  • Search actively for infection, bleeding, alcohol-related problems, constipation, medicines and portal-vein thrombosis.
  • Assess trajectory and organ failures because apparently modest observations may precede rapid deterioration.
02 · FIRST PRIORITIES

Act, escalate, reassess.

  1. Escalate early and use the current BSG/BASL and local decompensated-cirrhosis care bundle.
  2. Begin ABCDE assessment and send a structured initial investigation set, including cultures when infection is suspected.
  3. Perform timely diagnostic ascitic sampling when ascites is present unless a clinical contraindication exists.
  4. Address bleeding, infection, encephalopathy, acute kidney injury and alcohol withdrawal using local protocols and specialist input.
03 · ESCALATE NOW IF

Red flags that change pace.

  • Shock, active gastrointestinal bleeding or worsening encephalopathy
  • Acute kidney injury, severe hyponatraemia or respiratory compromise
  • Suspected spontaneous bacterial peritonitis or evolving multiorgan failure
04 · COMMON ERRORS

What makes care less safe.

  • Attributing confusion to hepatic encephalopathy without checking other causes
  • Missing infection because fever or leukocytosis is absent
  • Delaying ascitic sampling or specialist escalation
05 · STRUCTURED HANDOVER

Say the concern plainly.

Acute decompensated cirrhosis with [presenting complications], organ dysfunction [summary] and suspected precipitant [summary]. Care-bundle actions and ascitic/culture status are [list]. I need urgent hepatology and senior review.